The Next Generation of the Vaccine : NANOVACCINES
Vaccination has greatly improved human health. Despite of all improvements in this field, there is not an efficient vaccine for many diseases, and of the available ones, some could not produce a long-term immunity. The emergence of nanotechnology and its development has had a great influence on vaccine and its delivery systems. Recently, there have been many researches on the applicability of nano-structures as an efficient system for vaccine delivery, and the initial results have been promising. The main nano-particles used in vaccine delivery, including polymeric nano-particles, inorganic nano-particles, liposome, virus-like particles, and virosomes. Many polymeric nano-particles have been used for vaccine delivery, including gelatin, alginate hyaluronic acid and chitosan which the latter is the most used polymer in the field of vaccine formulations. Alginate-based nano-particles are another group of nano-particles that have attracted the attention of researchers for vaccine deliv...